GPR35 agonist 2
GPR35 agonist 2 (compound 11) is a potent agonist of GPR35, with EC50s of 26 and 3.2 nM in the β-arrestin and Ca2+ release assay, respectively[1].
Product Specifications
CAS Number
494191-73-0
UNSPSC
12352005
Target
Arrestin; GPR35
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/gpr35-agonist-2.html
Purity
98.61
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C(O)C1=CC=C(/C=C(SC(NC2=CC=CC=C2F)=N3)\C3=O)C=C1
Molecular Formula
C17H11FN2O3S
Molecular Weight
342.34
References & Citations
[1]Thimm D, et, al. 6-Bromo-8- (4-[ (3) H]methoxybenzamido) -4-oxo-4H-chromene-2-carboxylic Acid: a powerful tool for studying orphan G protein-coupled receptor GPR35. J Med Chem. 2013 Sep 12; 56 (17) : 7084-99.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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