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PF-05387252

PF-05387252 is a potent and selective IRAK4 inhibitor with the activity of inhibiting endogenous TLR signaling pathways. PF-05387252 has shown anti-inflammatory activity in experimental models and may have potential clinical application value in inhibiting psoriasis. Although PF-05387252 and its related compounds have shown anti-inflammatory effects in animal models, their efficacy in inhibiting psoriasis has not yet been verified[1].

Product Specifications

CAS Number

1604034-71-0

UNSPSC

12352005

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/pf-05387252.html

Smiles

N#CC1=CC2=C(C=C1)C3=C(C4=CC(OC)=C(C=C4N=C3)OCCCN5CCN(CC5)C)N2

Molecular Formula

C25H27N5O2

Molecular Weight

429.51

References & Citations

[1]Natural Modulators of Endosomal Toll-Like Receptor-Mediated Psoriatic Skin Inflammation

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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