Curcumin-d6
Curcumin-d6 (Diferuloylmethane-d6) is deuterium labeled Curcumin. Curcumin (Diferuloylmethane), a natural phenolic compound, is a p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. Curcumin is a photosensitizer against microorganisms. Curcumin shows inhibitory effects on NF-κB and MAPKs, and has diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification.
Product Specifications
CAS Number
1246833-26-0
Product Name Alternative
Diferuloylmethane-d6; Natural Yellow 3-d6; Turmeric yellow-d6
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Autophagy; Epigenetic Reader Domain; Ferroptosis; Histone Acetyltransferase; Influenza Virus; Isotope-Labeled Compounds; Keap1-Nrf2; Mitophagy
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Apoptosis; Autophagy; Epigenetics; NF-κB; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection; Metabolic Disease; Inflammation/Immunology
Purity
99.78
Solubility
DMSO : 100 mg/mL (ultrasonic; warming)
Smiles
O=C(CC(/C=C/C1=CC=C(O)C(OC([2H])([2H])[2H])=C1)=O)/C=C/C2=CC=C(O)C(OC([2H])([2H])[2H])=C2
Molecular Formula
C21H14D6O6
Molecular Weight
374.42
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
CBP/p300
Available Sizes
Frequently Asked Questions
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