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JAB1 Rabbit Monoclonal Antibody

JAB1 Rabbit Monoclonal Antibody

Product Specifications

Product Name Alternative

Peroxiredoxin-6; 1.11.1.15; 1-Cys peroxiredoxin; 1-Cys PRX; 24 kDa protein; Acidic calcium-independent phospholipase A2; aiPLA2; 3.1.1.-; Antioxidant protein 2; Liver 2D page spot 40; Non-selenium glutathione peroxidase; NSGPx; 1.11.1.9; Red blood cells page spot 12; PRDX6; AOP2, KIAA0106

UniProt

Q92905

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human JAB1 Probable protease subunit of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2.

Target

COP9 signalosome complex subunit 5

Clonality

Monoclonal

Clone

BCGGIX5

Conjugation

Unconjugated

Field of Research

Cancer Biology, Cell Biology, Epigenetics & Chromatin, Neuroscience, Protein Biochemistry, Signal Transduction

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Dilution

WB 1:500-2000 IHC 1:50-200 ICC/IF 1:50-200 IP 1:50

Form

Liquid

Molecular Weight

21 kDa

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Tested Applications

ICC, IF, IHC, IP, WB

Host or Source

Rabbit

Preservative

Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. *This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Isotype

Rabbit IgG

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