Zanidatamab

Zanidatamab (ZW25) is a humanised, bispecific monoclonal antibody targeting 2 distinct HER2 epitopes (ECD2 and ECD4) . Zanidatamab has anti-tumour activity[1].

Product Specifications

CAS Number

[2169946-15-8]

Product Name Alternative

ZW 25

UNSPSC

12352203

Target

EGFR

Type

Inhibitory Antibodies

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/zanidatamab.html

Purity

97.64

Solubility

10 mM in DMSO

Smiles

[Zanidatamab]

Molecular Weight

(148.28 kDa)

References & Citations

[1]Weisser N, et, al. Preclinical development of a novel biparatopic HER2 antibody with activity in low to high HER2 expressing cancers. Cancer Res. 2017:77 (13) .