Neurokinin A (TFA)

Neurokinin A TFA (Substance K TFA), a peptide neurotransmitter of the tachykinin family, acts via the NK-2 receptor. Neurokinin A acts as a major mediator in human airway and gastrointestinal tissues[1].

Product Specifications

CAS Number

[2828433-19-6]

Product Name Alternative

Substance K (TFA) ; Neurokinin α (TFA) ; Neuromedin L (TFA) ; NKA (TFA)

UNSPSC

12352209

Target

Neurokinin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/neurokinin-a-tfa.html

Purity

99.02

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)

Smiles

O=C(C(F)(F)F)O.CSCC[C@@H](C(N)=O)NC([C@@H](NC(CNC([C@H](C(C)C)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]([C@H](O)C)NC([C@@H](NC([C@H](CC1=CN=CN1)N)=O)CCCCN)=O)=O)CC(O)=O)=O)CO)=O)CC2=CC=CC=C2)=O)=O)=O)CC(C)C)=O

Molecular Formula

C52H81N14F3O16S

Molecular Weight

1247.34

References & Citations

[1]Gerard NP, et al. The human neurokinin A (substance K) receptor. Molecular cloning of the gene, chromosome localization, and isolation of cDNA from tracheal and gastric tissues. J Biol Chem. 1990 Nov 25;265 (33) :20455-62.