Levomefolic acid
Levomefolic acid (L-5-MTHF) is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements[1][2].
Product Specifications
CAS Number
31690-09-2
Product Name Alternative
L-5-MTHF
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
DNA/RNA Synthesis; Endogenous Metabolite; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/Levomefolic-acid.html
Purity
98.55
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 2.08 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)CC[C@@H](C(O)=O)NC(C1=CC=C(NC[C@@H]2N(C)C3=C(NC(N)=NC3=O)NC2)C=C1)=O
Molecular Formula
C20H25N7O6
Molecular Weight
459.46
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Citation 01
Naunyn Schmiedebergs Arch Pharmacol. 2025 Nov 18.|Oncogene. 2025 May;44 (16) :1078-1092.|J Mol Med (Berl) . 2019 Aug;97 (8) :1183-1193.
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