DOTAGA.(SA.FAPi)2 analogue (TFA)
Product Specifications
UNSPSC Description
DOTAGA.(SA.FAPi)2 analogue TFA is a DOTAGA.(SA.FAPi)2 TFA (HY-164364A) analogue, in which the ligand and the chelator are identical to those of DOTAGA.(SA.FAPi)2 TFA. DOTAGA.(SA.FAPi)2 TFA is a potent dimeric fibroblast-activation protein inhibitor (FAPi)[1].
Target Antigen
FAP
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dotaga-sa-fapi-2-analogue-tfa.html
Smiles
OC(C(F)(F)F)=O.O=C(O)CN1CCN(C(CCC(NCCNC(C2=O)=C(NCCCCOC3=CC4=C(N=CC=C4C(NCC(N5[C@H](C#N)CC(C5)(F)F)=O)=O)C=C3)C2=O)=O)C(O)=O)CCN(CCN(CC1)CCNCCNC(C6=O)=C(NCCCCOC7=CC8=C(N=CC=C8C(NCC(N9[C@H](C#N)CC(C9)(F)F)=O)=O)C=C7)C6=O)CC(O)=O
Molecular Weight
1679.61
References & Citations
[1]Tilman Läppchen, et al. Tailoring Fibroblast-Activation Protein Targeting for Theranostics: A Comparative Preclinical Evaluation of the 68Ga- and 177Lu-Labeled Monomeric and Dimeric Fibroblast-Activation Protein Inhibitors DOTA.SA.FAPi and DOTAGA.(SA.FAPi)2. Molecules. 2024 Jun 28;29(13):3093.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-164364B/DOTAGA-SA-FAPi-2-analogue-TFA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-164364B/
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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