Phospho-Akt1 (Ser473) Rabbit FITC Conjugate

<strong>Phospho-Akt1 (Ser473) Rabbit FITC Conjugate </strong>_x000D_ <strong>Catalog number:</strong> B2018508_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 25 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8°C_x000D_ <strong>Keywords:</strong> RAC-alpha serine/threonine-protein kinase, Protein kinase B, PKB_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Liu N, Jiang L, Sun X, Yao X, Zhai X, Liu X, Wu X, Bai Y, Wang S, Yang G. Mono-(2-ethylhexyl) phthalate induced ROS-dependent autophagic cell death in human vascular endothelial cells Toxicol In Vitro. 2017 Oct;44:49-56._x000D_ 2: Aleskandarany MA, Rakha EA, Ahmed MA, Powe DG, Ellis IO, Green AR. Clinicopathologic and molecular significance of phospho-Akt expression in early invasive breast cancer Breast Cancer Res Treat. 2011 Jun;127(2):407-16._x000D_ 3: McKenna M, Balasuriya N, Zhong S, Li SS, O'Donoghue P. Phospho-Form Specific Substrates of Protein Kinase B (AKT1) Front Bioeng Biotechnol. 2021 Feb 3;8:619252._x000D_ 4: Siddika T, Shao R, Heinemann IU, O'Donoghue P. Delivery of AKT1 phospho-forms to human cells reveals differential substrate selectivity IUBMB Life. 2024 Sep;76(9):632-646._x000D_ 5: Siddika T, Balasuriya N, Frederick MI, Rozik P, Heinemann IU, O'Donoghue P. Delivery of Active AKT1 to Human Cells Cells. 2022 Nov 29;11(23):3834._x000D_ 6: Zhang H. NFluc-FHA2-Aktpep-CFluc 2008 Nov 14 [updated 2008 Dec 22]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013._x000D_ 7: Balasuriya N, Davey NE, Johnson JL, Liu H, Biggar KK, Cantley LC, Li SS, O'Donoghue P. Phosphorylation-dependent substrate selectivity of protein kinase B (AKT1) J Biol Chem. 2020 Jun 12;295(24):8120-8134._x000D_ 8: Ouyang YB, Zhang XH, He QP, Wang GX, Siesjö BK, Hu BR. Differential phosphorylation at Ser473 and Thr308 of Akt-1 in rat brain following hypoglycemic coma Brain Res. 2000 Sep 8;876(1-2):191-5._x000D_ 9: Neves SP, Bomfim LM, Kataura T, Carvalho SG, Nogueira ML, Dias RB, Valverde LF, Gurgel Rocha CA, Soares MBP, Silva MMD, Batista AA, Korolchuk VI, Bezerra DP. Ruthenium complex containing 1,3-thiazolidine-2-thione inhibits hepatic cancer stem cells by suppressing Akt/mTOR signalling and leading to apoptotic and autophagic cell death Biomed Pharmacother. 2024 Aug;177:117059._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/15289328">10: Kreisberg JI, Malik SN, Prihoda TJ, Bedolla RG, Troyer DA, Kreisberg S, Ghosh PM. Phosphorylation of Akt (Ser473) is an excellent predictor of poor clinical outcome in prostate cancer Cancer Res. 2004 Aug 1;64(15):5232-6. </a>_x000D_ _x000D_ <strong>Products Related to Phospho-Akt1 (Ser473) Rabbit FITC Conjugate can be found at</strong> <a href="https://moleculardepot.com/product-category/Conjugates/"> Conjugates</a>