9-Hydroxycalabaxanthone

9-Hydroxycalabaxanthone (Xanthone I) is a known xanthone isolated from Garcinia mangostana Linn. 9-Hydroxycalabaxanthone has quorum-sensing inhibitory, anti-microbial, and anti-malarial activities (IC50=1.2-1.5 μM) [1].

Product Specifications

CAS Number

[35349-68-9]

Product Name Alternative

Xanthone I

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Bacterial; Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/9-hydroxycalabaxanthone.html

Purity

99.14

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C1C2=C(OC3=C1C(C/C=C(C)\C)=C(OC)C(O)=C3)C=C4C(C=CC(C)(C)O4)=C2O

Molecular Formula

C24H24O6

Molecular Weight

408.44

Precautions

H315, H319

References & Citations

[1]Gamal A Mohamed, et al. Mangostanaxanthones I and II, New Xanthones From the Pericarp of Garcinia Mangostana. Fitoterapia. 2014 Oct;98:215-21.|[2]Wanna Chaijaroenkul, et al. The in Vitro Antimalarial Interaction of 9-hydroxycalabaxanthone and α-mangostin With mefloquine/artesunate. Acta Parasitol. 2014 Mar;60 (1) :105-11.