9-Hydroxycalabaxanthone
9-Hydroxycalabaxanthone (Xanthone I) is a known xanthone isolated from Garcinia mangostana Linn. 9-Hydroxycalabaxanthone has quorum-sensing inhibitory, anti-microbial, and anti-malarial activities (IC50=1.2-1.5 μM) [1].
Product Specifications
CAS Number
35349-68-9
Product Name Alternative
Xanthone I
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Bacterial; Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/9-hydroxycalabaxanthone.html
Purity
99.14
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1C2=C(OC3=C1C(C/C=C(C)\C)=C(OC)C(O)=C3)C=C4C(C=CC(C)(C)O4)=C2O
Molecular Formula
C24H24O6
Molecular Weight
408.44
Precautions
H315, H319
References & Citations
[1]Gamal A Mohamed, et al. Mangostanaxanthones I and II, New Xanthones From the Pericarp of Garcinia Mangostana. Fitoterapia. 2014 Oct;98:215-21.|[2]Wanna Chaijaroenkul, et al. The in Vitro Antimalarial Interaction of 9-hydroxycalabaxanthone and α-mangostin With mefloquine/artesunate. Acta Parasitol. 2014 Mar;60 (1) :105-11.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Plasmodium
Available Sizes
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