LDC000067
LDC000067 is a highly specific CDK9 inhibitor with an IC50 value of 44±10 nM in vitro.
Product Specifications
CAS Number
[1073485-20-7]
Product Name Alternative
LDC067
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; CDK
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/LDC000067.html
Purity
99.00
Solubility
DMSO : ≥ 47 mg/mL
Smiles
O=S(CC1=CC=CC(NC2=NC=NC(C3=CC=CC=C3OC)=C2)=C1)(N)=O
Molecular Formula
C18H18N4O3S
Molecular Weight
370.43
Precautions
H302, H315, H319, H335
References & Citations
[1]Albert TK, et al. Characterization of molecular and cellular functions of the cyclin-dependent kinase CDK9 using a novel specific inhibitor. Br J Pharmacol. 2014 Jan;171 (1) :55-68.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK1; CDK2; CDK4; CDK9
Available Sizes
Curated Selection
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