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FAUC 346

FAUC 346, a highly selective D3 partial agonist (EC50 = 1.5 nM) [1][2].

Product Specifications

CAS Number

474432-65-0

UNSPSC

12352005

Target

Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/fauc-346.html

Purity

99.90

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CC2=CC=CC=C2S1)NCCCCN3CCN(C4=CC=CC=C4OC)CC3

Molecular Formula

C24H29N3O2S

Molecular Weight

423.57

References & Citations

[1]Bertrand Kuhnast, et al. Synthesis and radiolabeling of N-[4-[4- (2-[11C]methoxyphenyl) piperazin-1-yl]butyl]benzo[b]thiophene-2-carboxamide -- a potential radiotracer for D3 receptor imaging with PET. Nucl Med Biol. 2006 Aug;33 (6) :785-95.|[2]Carsten Hocke, et al. 18F-Labeled FAUC 346 and BP 897 derivatives as subtype-selective potential PET radioligands for the dopamine D3 receptor. ChemMedChem. 2008 May;3 (5) :788-93.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

D3 Receptor

Available Sizes

Frequently Asked Questions

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