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UFP-101 (TFA)

UFP-101 TFA is a potent, selective, and competitive antagonist of the N/OFQ peptide (NOP) receptor, with a pKi of 10.24. UFP-101 TFA displays >3000-fold selectivity over δ, μ and κ opioid receptors. UFP-101 TFA shows antidepressant-like effect[1][2].

Product Specifications

UNSPSC

12352209

Target

Opioid Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ufp-101-tfa.html

Purity

99.36

Solubility

H2O : 130 mg/mL (ultrasonic)

Smiles

OC(C(F)(F)F)=O.NC(CC[C@@H](C(N)=O)NC([C@H](CC(N)=O)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@H](C)NC([C@H](CO)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@H](C)NC(CNC([C@H]([C@H](O)C)NC([C@@H](NC(CNC(CNC(CNCC1=CC=CC=C1)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C84H139F3N32O23

Molecular Weight

2022.19

References & Citations

114152

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P1299A/UFP-101-TFA-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P1299A/UFP-101-TFA-SDS-MedChemExpress.pdf

Scientific Category

Peptides

Clinical Information

No Development Reported

Isoform

NOP Receptor/ORL1

Available Sizes

Curated Selection

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