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CAY10502

CAY10502 is a potent, calcium-dependent cytosolic phospholipase A2 α (cPLA2α) inhibitor with an IC50 of 4.3 nM for isolated enzyme. CAY10502 can be used in the research of retinopathy and inflammatory diseases[1][2][3].

Product Specifications

CAS Number

888320-29-4

Product Name Alternative

MLN7243

UNSPSC

12352005

Hazard Statement

H302-H312-H315-H319-H332

Target

Phospholipase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cay10502.html

Purity

99.0

Solubility

DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C1=CN(CC(COC2=CC=C(OCCCCCCCCCC)C=C2)=O)C3=C1C=C(C(O)=O)C=C3)OC

Molecular Formula

C30H37NO7

Molecular Weight

523.62

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Pohjala L L, et al. Interference by bovine serum albumin in PED6 based phospholipase A2 screening assays[J]. Die Pharmazie, 2012.|[2]Barnett JM, et al. Role of cytosolic phospholipase A (2) in retinal neovascularization. Invest Ophthalmol Vis Sci. 2010;51 (2) :1136-1142.|[3]Cui Y, et al. Exposure to extremely low-frequency electromagnetic fields inhibits T-type calcium channels via AA/LTE4 signaling pathway. Cell Calcium. 2014 Jan;55 (1) :48-58.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Phospholipase A

Available Sizes

Frequently Asked Questions

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