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Dehydrodiisoeugenol

Product Specifications

UNSPSC Description

Dehydrodiisoeugenol is isolated from Myristica fragrans Houtt, shows anti-inflammatory and anti-bacterial actions[1]. Dehydrodiisoeugenol inhibits LPS- stimulated NF-κB activation and cyclooxygenase (COX)-2 gene expression in murine macrophages[2].

Target Antigen

Bacterial; COX; NF-κB

Type

Natural Products

Related Pathways

Anti-infection;Immunology/Inflammation;NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/dehydrodiisoeugenol.html

Purity

99.98

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC1=CC=C(C2OC3=C(OC)C=C(/C=C/C)C=C3C2C)C=C1OC

Molecular Weight

326.39

References & Citations

[1]Murakami Y, et al. Dehydrodiisoeugenol, an isoeugenol dimer, inhibits lipopolysaccharide-stimulated nuclear factor kappa B activation and cyclooxygenase-2 expression in macrophages. Arch Biochem Biophys. 2005 Feb 15;434(2):326-32.|[2]Lv QQ, et al. Metabolic profiling of dehydrodiisoeugenol using xenobiotic metabolomics. J Pharm Biomed Anal. 2017 Oct 25;145:725-733.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-N0589/Dehydrodiisoeugenol-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-N0589/Dehydrodiisoeugenol-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

2680-81-1

Available Sizes

Curated Selection

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