Dehydrodiisoeugenol
Product Specifications
UNSPSC Description
Dehydrodiisoeugenol is isolated from Myristica fragrans Houtt, shows anti-inflammatory and anti-bacterial actions[1]. Dehydrodiisoeugenol inhibits LPS- stimulated NF-κB activation and cyclooxygenase (COX)-2 gene expression in murine macrophages[2].
Target Antigen
Bacterial; COX; NF-κB
Type
Natural Products
Related Pathways
Anti-infection;Immunology/Inflammation;NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/dehydrodiisoeugenol.html
Purity
99.98
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=CC=C(C2OC3=C(OC)C=C(/C=C/C)C=C3C2C)C=C1OC
Molecular Weight
326.39
References & Citations
[1]Murakami Y, et al. Dehydrodiisoeugenol, an isoeugenol dimer, inhibits lipopolysaccharide-stimulated nuclear factor kappa B activation and cyclooxygenase-2 expression in macrophages. Arch Biochem Biophys. 2005 Feb 15;434(2):326-32.|[2]Lv QQ, et al. Metabolic profiling of dehydrodiisoeugenol using xenobiotic metabolomics. J Pharm Biomed Anal. 2017 Oct 25;145:725-733.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N0589/Dehydrodiisoeugenol-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N0589/Dehydrodiisoeugenol-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2680-81-1
Available Sizes
Curated Selection
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