Soxataltinib
Soxataltinib (example 7) is a potent inhibitor of RET-kinase, with the IC50 of 0.601 nM. Soxataltinib plays an important role in cancer research[1].
Product Specifications
CAS Number
2546116-88-3
UNSPSC
12352005
Target
RET
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/soxataltinib.html
Smiles
N#CC1=C2C(C3=CC=C(N4CC5N(C(C5)C4)CC6=CN=C(C=C6)OC)N=C3)=CC(N7CC(C)(C7)O)=CN2N=C1
Molecular Formula
C29H30N8O2
Molecular Weight
522.60
References & Citations
[1]Shouyao Holdings (Beijing) Co., Ltd. Preparation of piperazine-containing pyrazolopyridine carbonitrile derivative as RET selective inhibitors for treatment of RET-related diseases. China, CN112209925 A 2021-01-12
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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