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Tertiapin-Q

Product Specifications

UNSPSC Description

Tertiapin-Q is a highly selective blocker of GIRK1/4 heterodimer and ROMK1 (Kir1.1).

Target Antigen

Potassium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Tertiapin-Q.html

Purity

99.84

Solubility

H2O : 50 mg/mL (ultrasonic)

Smiles

[Ala-Leu-Cys-Asn-Cys-Asn-Arg-Ile-Ile-Ile- Pro-His-Gln-Cys-Trp-Lys-Lys-Cys-Gly-Lys- Lys-NH2(Disulfide bridge: Cys3-Cys14, Cys5-Cys18)]

Molecular Weight

2452.00

References & Citations

[1]Picton LD, et al. Mechanisms underlying the endogenous dopaminergic inhibition of spinal locomotor circuit function in Xenopus tadpoles. Sci Rep. 2016 Oct 20;6:35749.|[2]Günther T, et al. Research Resource: Real-Time Analysis of Somatostatin and Dopamine Receptor Signaling in Pituitary Cells Using a Fluorescence-Based Membrane Potential Assay. Mol Endocrinol. 2016 Apr;30(4):479-90.|[3]Chiba T, et al. Influences of rapid pacing-induced electrical remodeling on pharmacological manipulation of the atrial refractoriness in rabbits. J Pharmacol Sci. 2016 Mar;130(3):170-6.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P1275/Tertiapin-Q-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P1275/Tertiapin-Q-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

910044-56-3

Available Sizes

Curated Selection

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