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KMT5A/SETD8/Pr-SET7/SET7 Rabbit Monoclonal Antibody

KMT5A/SETD8/Pr-SET7/SET7 Rabbit Monoclonal Antibody

Product Specifications

Product Name Alternative

Kinesin-like protein KIFC1; Kinesin-like protein 2; Kinesin-related protein HSET; KIFC1; HSET, KNSL2

UniProt

Q9NQR1

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human KMT5A / SETD8 / Pr-SET7 Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1) . H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes.

Target

N-lysine methyltransferase KMT5A

Clonality

Monoclonal

Clone

BCFJQX33

Conjugation

Unconjugated

Field of Research

Epigenetics & Chromatin, Molecular Biology

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Dilution

WB 1:500-2000 FC 1:100

Form

Liquid

Molecular Weight

72 kDa

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Tested Applications

FC, WB

Host or Source

Rabbit

Preservative

Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. *This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Isotype

Rabbit IgG

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