SHC Rabbit Monoclonal Antibody
Anti-SHC Monoclonal Antibody. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Product Name Alternative
Cyclin-dependent kinase 9; 2.7.11.22; 2.7.11.23; C-2K; Cell division cycle 2-like protein kinase 4; Cell division protein kinase 9; Serine/threonine-protein kinase PITALRE; Tat-associated kinase complex catalytic subunit; CDK9; CDC2L4, TAK
UniProt
P29353
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human SHC Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals.
Target
SHC-transforming protein 1
Clonality
Monoclonal
Clone
BCFHKX31
Conjugation
Unconjugated
Field of Research
Cardiovascular Research, Cell Biology, Neuroscience, Signal Transduction
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Dilution
WB 1:500-2000 IHC 1:50-200 ICC/IF 1:50-200 FC 1:50
Form
Liquid
Molecular Weight
65-70 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
FC, ICC, IF, IHC, WB
Host or Source
Rabbit
Preservative
Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. *This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.
Isotype
Rabbit IgG
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