Securin Rabbit Monoclonal Antibody
Anti-Securin Monoclonal Antibody. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human.
Product Specifications
Product Name Alternative
Actin-related protein 2/3 complex subunit 5; Arp2/3 complex 16 kDa subunit; p16-ARC; ARPC5; ARC16
UniProt
O95997
Reactivity
Human
Immunogen
A synthesized peptide derived from human Securin Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes.
Target
Securin
Clonality
Monoclonal
Clone
BCFHJX38
Conjugation
Unconjugated
Field of Research
Cancer Biology, Cell Biology, Epigenetics & Chromatin, Protein Biochemistry, Signal Transduction
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Dilution
WB 1:500-2000 IHC 1:50-200 ICC/IF 1:50-200 IP 1:30 FC 1:50
Form
Liquid
Molecular Weight
26 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
FC, ICC, IF, IHC, IP, WB
Host or Source
Rabbit
Preservative
Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. *This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.
Isotype
Rabbit IgG
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