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TRIM25 Rabbit Monoclonal Antibody

Anti-TRIM25 Monoclonal Antibody. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Product Name Alternative

Peptidyl-prolyl cis-trans isomerase B; PPIase B; 5.2.1.8; CYP-S1; Cyclophilin B; Rotamase B; S-cyclophilin; SCYLP; PPIB; CYPB

UniProt

Q14258

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human TRIM25 Functions as an ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection.

Target

E3 ubiquitin/ISG15 ligase TRIM25

Clonality

Monoclonal

Clone

BCFHIX42

Conjugation

Unconjugated

Field of Research

Cell Biology, Epigenetics & Chromatin, Infectious Disease & Virology, Protein Biochemistry, Signal Transduction

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Dilution

WB 1:1000-5000 IHC 1:50-200 ICC/IF 1:50-200 IP 1:50 FC 1:60

Form

Liquid

Molecular Weight

71 kDa

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Tested Applications

FC, ICC, IF, IHC, IP, WB

Host or Source

Rabbit

Preservative

Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. *This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Isotype

Rabbit IgG

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