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Landipirdine

Landipirdine (RO5025181; SYN120) is an orally active 5-HT6 and 5-HT2A receptors antagonist. Landipirdine can be used for the study of Parkinson disease[1].

Product Specifications

Product Name Alternative

RO5025181; SYN120

UNSPSC

12352005

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/landipirdine.html

Purity

99.80

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

NC(NC[C@H]1C2=CC=C(S(=O)(C3=CC(F)=CC=C3)=O)C=C2CCC1)=O

Molecular Formula

C18H19FN2O3S

Molecular Weight

362.42

References & Citations

[1]Fernandez HH, et al. Safety, tolerability, and preliminary efficacy of SYN120, a dual 5-HT6/5-HT2A antagonist, for the treatment of Parkinson disease dementia: A randomized, controlled, proof-of-concept trial. Parkinsonism Relat Disord. 2023 Sep;114:105511.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-109036/Landipirdine-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-109036/Landipirdine-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

Phase 2

Isoform

5-HT2 Receptor;5-HT6 Receptor

CAS Number

[1000308-25-7]

Available Sizes

Curated Selection

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