EMD 57439
EMD 57439 is a selective PDE-III inhibitor. EMD 57439 does not significantly increase c-AMP concentration and has little effect on Ca (50) [1].
Product Specifications
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/emd-57439.html
Solubility
10 mM in DMSO
Smiles
O=C1S[C@H](C(C2=CC3=C(C=C2)N(CCC3)C(C4=CC=C(C(OC)=C4)OC)=O)=NN1)C
Molecular Formula
C22H23N3O4S
Molecular Weight
425.50
References & Citations
[1]Kusakari Y, et al. Use of the Ca-shortening curve to estimate the myofilament responsiveness to Ca2+ in tetanized rat ventricular myocytes. J Physiol Sci. 2006 Jun;56 (3) :219-26.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-114990/EMD-57439-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-114990/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
CAS Number
[148714-88-9]
Available Sizes
Curated Selection
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