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STK683963

STK683963 is a strong activator of cellular ATG4B activity. STK683963 can act as a mediator of redox-regulation of ATG4B in cells. STK683963 can be used for the research of cancer[1].

Product Specifications

CAS Number

[370073-65-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Atg4; Autophagy

Type

Reference compound

Related Pathways

Autophagy

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/stk683963.html

Purity

99.41

Solubility

10 mM in DMSO

Smiles

O=C1C=C(O)C(SC(NC2=CC=C(F)C=C2)=N3)=C3N1

Molecular Formula

C12H8FN3O2S

Molecular Weight

277.27

Precautions

H302, H315, H319, H335

References & Citations

[1]Niccolo Pengo, et al. Identification of Kinases and Phosphatases That Regulate ATG4B Activity by siRNA and Small Molecule Screening in Cells. Front Cell Dev Biol. 2018 Nov 1;6:148.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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