STK683963
STK683963 is a strong activator of cellular ATG4B activity. STK683963 can act as a mediator of redox-regulation of ATG4B in cells. STK683963 can be used for the research of cancer[1].
Product Specifications
CAS Number
[370073-65-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Atg4; Autophagy
Type
Reference compound
Related Pathways
Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/stk683963.html
Purity
99.41
Solubility
10 mM in DMSO
Smiles
O=C1C=C(O)C(SC(NC2=CC=C(F)C=C2)=N3)=C3N1
Molecular Formula
C12H8FN3O2S
Molecular Weight
277.27
Precautions
H302, H315, H319, H335
References & Citations
[1]Niccolo Pengo, et al. Identification of Kinases and Phosphatases That Regulate ATG4B Activity by siRNA and Small Molecule Screening in Cells. Front Cell Dev Biol. 2018 Nov 1;6:148.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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TNKS, NT (TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1, Tankyrase-1, ADP-ribosyltransferase diphtheria toxin-like 5, Poly [ADP-ribose] polymerase 5A, TNKS-1, TRF1-interacting ankyrin-related ADP-ribose polymerase, Tankyrase I) (APC) discontinued
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