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MacroH2A.1 H2AFY Rabbit Monoclonal Antibody

MacroH2A.1 H2AFY Rabbit Monoclonal Antibody

Product Specifications

Product Name Alternative

Glycine--tRNA ligase; 3.6.1.17; 6.1.1.14; Diadenosine tetraphosphate synthetase; AP-4-A synthetase; Glycyl-tRNA synthetase; GlyRS; GARS

UniProt

O75367

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human macroH2A.1 Involved in stable X chromosome inactivation. Inhibits the binding of transcription factors and interferes with the activity of remodeling SWI/SNF complexes. Inhibits histone acetylation by EP300 and recruits class I HDACs, which induces an hypoacetylated state of chromatin.

Target

Core histone macro-H2A.1

Clonality

Monoclonal

Clone

BCFFKX0

Conjugation

Unconjugated

Field of Research

Epigenetics & Chromatin

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Dilution

WB 1:500-2000 IHC 1:50-200 ICC/IF 1:50-200

Form

Liquid

Molecular Weight

38 kDa

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Tested Applications

ICC, IF, IHC, WB

Host or Source

Rabbit

Preservative

Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. *This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Isotype

Rabbit IgG

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