MacroH2A.1 H2AFY Rabbit Monoclonal Antibody
MacroH2A.1 H2AFY Rabbit Monoclonal Antibody
Product Specifications
Product Name Alternative
Glycine--tRNA ligase; 3.6.1.17; 6.1.1.14; Diadenosine tetraphosphate synthetase; AP-4-A synthetase; Glycyl-tRNA synthetase; GlyRS; GARS
UniProt
O75367
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human macroH2A.1 Involved in stable X chromosome inactivation. Inhibits the binding of transcription factors and interferes with the activity of remodeling SWI/SNF complexes. Inhibits histone acetylation by EP300 and recruits class I HDACs, which induces an hypoacetylated state of chromatin.
Target
Core histone macro-H2A.1
Clonality
Monoclonal
Clone
BCFFKX0
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Dilution
WB 1:500-2000 IHC 1:50-200 ICC/IF 1:50-200
Form
Liquid
Molecular Weight
38 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ICC, IF, IHC, WB
Host or Source
Rabbit
Preservative
Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. *This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.
Isotype
Rabbit IgG
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