JI-101
JI-101 is an orally available multi-kinase inhibitor of VEGFR2, PDGFRβ and EphB4 with potent anti-cancer activity.
Product Specifications
CAS Number
[900573-88-8]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Ephrin Receptor; PDGFR; VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/JI-101.html
Purity
99.78
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(NC1=CC(Br)=CC=C1OC)NC2=CC=CC3=C2C=CN3CC4=CC(N)=NC=C4
Molecular Formula
C22H20BrN5O2
Molecular Weight
466.33
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-16265/JI-101-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-16265/JI-101-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
PDGFRβ; VEGFR2/KDR/Flk-1
Available Sizes
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