JI-101
Product Specifications
UNSPSC Description
JI-101 is an orally available multi-kinase inhibitor of VEGFR2, PDGFRβ and EphB4 with potent anti-cancer activity.
Target Antigen
Ephrin Receptor; PDGFR; VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/JI-101.html
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(NC1=CC(Br)=CC=C1OC)NC2=CC=CC3=C2C=CN3CC4=CC(N)=NC=C4
Molecular Weight
466.33
References & Citations
[1]Gurav SD, et al. Pharmacokinetics, tissue distribution and identification of putative metabolites of JI-101 - a novel triple kinase inhibitor in rats. Arzneimittelforschung. 2012 Jan;62(1):27-34.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-16265/JI-101-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-16265/JI-101-SDS-MedChemExpress.pdf
Clinical Information
Phase 2
CAS Number
900573-88-8
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![ZNF583 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI3E2]](https://cdn.genprice.uk/products/937/6868c409994c49e6dc4048e9/imageurl/ta810557bm.webp)
TA810557BM 100 µL
ZNF583 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI3E2]
Ask
View Details 