MALT1 Rabbit Monoclonal Antibody
MALT1 Rabbit Monoclonal Antibody
Product Specifications
Product Name Alternative
E3 ubiquitin-protein ligase NEDD4-like; 6.3.2.-; NEDD4.2; Nedd4-2; NEDD4L; KIAA0439, NEDL3
UniProt
Q9UDY8
Reactivity
Human
Immunogen
A synthesized peptide derived from human MALT1 Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion.
Target
Mucosa-associated lymphoid tissue lymphoma translocation protein 1
Clonality
Monoclonal
Clone
BCFFCX35
Conjugation
Unconjugated
Field of Research
Cell Biology, Immunology & Inflammation, Signal Transduction
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Dilution
WB 1:500-2000 ICC/IF 1:50-200 FC 1:20
Form
Liquid
Molecular Weight
40-48 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
FC, ICC, IF, WB
Host or Source
Rabbit
Preservative
Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. *This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.
Isotype
Rabbit IgG
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