N-Acetyl-D-glucosamine

N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose), the D isomer of N-acetylglucosamine, is an orally active monosaccharide derivative of glucose with anti-tumor and anti-inflammation properties. N-Acetyl-D-Glucosamine is also a bacterial metabolite, which is found in Escherichia coli. N-Acetyl-D-Glucosamine can induce yeast-mycelial conversion in Candida albicans. N-Acetyl-D-Glucosamine also enhances healing of cartilaginous injuries in rabbits[1][2][3].

Product Specifications

CAS Number

[7512-17-6]

Product Name Alternative

N-Acetyl-2-amino-2-deoxy-D-glucose

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Drug Derivative; Drug Isomer; Endogenous Metabolite; Interleukin Related

Type

Natural Products

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; Others

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Cancer; Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/N-Acetyl-D-glucosamine.html

Purity

99.20

Solubility

DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 100 mg/mL (ultrasonic)

Smiles

O=C[C@@H]([C@@H](O)[C@H](O)[C@H](O)CO)NC(C)=O

Molecular Formula

C8H15NO6

Molecular Weight

221.21

Precautions

H302, H315, H319, H335

References & Citations

[1]Simonetti N, et al. Yeast-mycelial conversion induced by N-acetyl-D-glucosamine in Candida albicans. Nature. 1974 Jul 26;250 (464) :344-6.|[2]Masuda S, et al. Anti-tumor properties of orally administered glucosamine and N-acetyl-D-glucosamine oligomers in a mouse model. Carbohydr Polym. 2014 Oct 13;111:783-7.|[3]Tamai Y, et al. Enhanced healing of cartilaginous injuries by N-acetyl-d-glucosamine and glucuronic acid[J]. Carbohydrate Polymers, 2003, 54 (2) : 251-262.