CD46, Human (HEK293, hFc)

CD46 Protein serves as a cofactor for complement factor I, safeguarding cells against complement-induced harm. It aids in sperm-oocyte fusion and acts as a T-cell costimulatory factor, facilitating the formation of T-regulatory 1 cells. These cells secrete interleukin-10, suppressing immune responses and preventing autoimmunity. Pathogens can exploit CD46's immune regulation abilities to induce an immunosuppressive state in T-cells. CD46 Protein, Human (HEK293, hFc) is the recombinant human-derived CD46 protein, expressed by HEK293 , with C-hFc labeled tag.

CEEPPTFEAM ELIGKPKPYY EIGERVDYKC KKGYFYIPPL ATHTICDRNH TWLPVSDDAC YRETCPYIRD PLNGQAVPAN GTYEFGYQMH FICNEGYYLI GEEILYCELK GSVAIWSGKP PICEKVLCTP PPKIKNGKHT FSEVEVFEYL DAVTYSCDPA PGPDPFSLIG ESTIYCGDNS VWSRAAPECK VVKCRFPVVE NGKQISGFGK KFYYKATVMF ECDKGFYLDG SDTIVCDSNS TWDPPVPKCL KVLPPSSTKP PALSHSVSTS STTKSPASSA SGPRPTYKPP VSNY