Phenytoin (Standard)

Phenytoin (Standard) is the analytical standard of Phenytoin. This product is intended for research and analytical applications. Phenytoin (5,5-Diphenylhydantoin) is a potent Voltage-gated Na+ channels (VGSCs) blocker. Phenytoin has antiepileptic activity and reduces breast tumour growth and metastasis in mice[1][2].

Product Specifications

CAS Number

[57-41-0]

Product Name Alternative

5,5-Diphenylhydantoin (Standard)

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335-H350-H360

Target

Reference Standards; Sodium Channel; Virus Protease

Type

Reference Standards

Related Pathways

Anti-infection; Membrane Transporter/Ion Channel; Others

Field of Research

Neurological Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/phenytoin-standard.html

Purity

99.87

Smiles

O=C1NC(C(C2=CC=CC=C2)(C3=CC=CC=C3)N1)=O

Molecular Formula

C15H12N2O2

Molecular Weight

252.27

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Rogawski, M.A. and W. Loscher, The neurobiology of antiepileptic drugs. Nat Rev Neurosci, 2004. 5 (7) : p. 553-64.|[2]Porter, R.J., et al., Mechanisms of action of antiseizure drugs. Handb Clin Neurol, 2012. 108: p. 663-81.|[3]Balaji, S., Medical therapy for sudden death. Pediatr Clin North Am, 2004. 51 (5) : p. 1379-87.|[4]Michaela Nelson, et al. The sodium channel-blocking antiepileptic drug phenytoin inhibits breast tumour growth and metastasis. Mol Cancer. 2015 Jan 27;14 (1) :13.