LSD2/AOF1 Rabbit Monoclonal Antibody
LSD2/AOF1 Rabbit Monoclonal Antibody
Product Specifications
Product Name Alternative
Calponin-1; Basic calponin; Calponin H1, smooth muscle; CNN1
UniProt
Q8NB78
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human LSD2 / AOF1 Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed.
Target
Lysine-specific histone demethylase 2
Clonality
Monoclonal
Clone
BCFCIX33
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin, Metabolism Research
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Dilution
WB 1:500-2000 ICC/IF 1:50-200 IP 1:20 FC 1:20
Form
Liquid
Molecular Weight
93 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
FC, ICC, IF, IP, WB
Host or Source
Rabbit
Preservative
Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. *This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.
Isotype
Rabbit IgG
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