2-Amino-9-β-D-ribofuranosylpurine
(2R,3R,4S,5R) -2- (2-amino-9H-purin-9-yl) -5- (hydroxymethyl) tetrahydrofuran-3,4-diol (9-pentofuranosyl-9H-purin-2-amine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[4546-54-7]
Product Name Alternative
9-Pentofuranosyl-9H-purin-2-amine
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/2-amino-9-β-d-ribofuranosylpurine.html
Purity
99.71
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C=NC3=CN=C(N)N=C32
Molecular Formula
C10H13N5O4
Molecular Weight
267.24
Precautions
H315, H319
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Browse additional items from our catalog
Hamster Matrix metalloproteinase 9 (MMP9) ELISA K
Hamster Matrix metalloproteinase 9 (MMP9) ELISA K
Hamster Matrix metalloproteinase 9 (MMP9) ELISA K
Hamster Matrix metalloproteinase 9 (MMP9) ELISA K