Carmoxirole (hydrochloride)
Carmoxirole hydrochloride (EMD 45609 hydrochloride) is a selective, peripherally acting dopamine D2 receptor agonist and exhibits antihypertensive activities in vivo[1].
Product Specifications
CAS Number
115092-85-8
Product Name Alternative
EMD 45609 (hydrochloride)
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/carmoxirole-hydrochloride.html
Concentration
10mM
Purity
99.82
Solubility
DMSO : 45 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
OC(C1=CC2=C(C=C1)NC=C2CCCCN3CCC(C4=CC=CC=C4)=CC3)=O.[H]Cl
Molecular Formula
C24H27ClN2O2
Molecular Weight
410.94
References & Citations
[1]Haase AF, et al. Neurochemical profile of EMD 45609 (carmoxirole), a dopamine DA2-receptor agonist. Naunyn Schmiedebergs Arch Pharmacol. 1991 Jun;343 (6) :588-94.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
D2 Receptor
Available Sizes
Frequently Asked Questions
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