Carmoxirole (hydrochloride)

Carmoxirole hydrochloride (EMD 45609 hydrochloride) is a selective, peripherally acting dopamine D2 receptor agonist and exhibits antihypertensive activities in vivo[1].

Product Specifications

CAS Number

[115092-85-8]

Product Name Alternative

EMD 45609 (hydrochloride)

UNSPSC

12352005

Target

Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/carmoxirole-hydrochloride.html

Concentration

10mM

Purity

99.82

Solubility

DMSO : 45 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

OC(C1=CC2=C(C=C1)NC=C2CCCCN3CCC(C4=CC=CC=C4)=CC3)=O.[H]Cl

Molecular Formula

C24H27ClN2O2

Molecular Weight

410.94

References & Citations

[1]Haase AF, et al. Neurochemical profile of EMD 45609 (carmoxirole), a dopamine DA2-receptor agonist. Naunyn Schmiedebergs Arch Pharmacol. 1991 Jun;343 (6) :588-94.