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NPD8733

NPD8733 is an inhibitor of cancer cell-enhanced fibroblast migration. NPD8733 specifically binds to valosin-containing protein (VCP) /p97, a member of the ATPase-associated with diverse cellular activities (AAA+) protein family. NPD8733 has the potential for the research of cancer diseases[1].

Product Specifications

CAS Number

696655-62-6

UNSPSC

12352005

Target

P97

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/npd8733.html

Purity

99.92

Solubility

DMSO : 116.67 mg/mL (ultrasonic)

Smiles

CC(NC1=C(C(C2=CC=C(OC)C=C2)=O)OC3=CC=CC=C13)=O

Molecular Formula

C18H15NO4

Molecular Weight

309.32

References & Citations

[1]Suvarna K, et al. A small-molecule ligand of valosin-containing protein/p97 inhibits cancer cell-accelerated fibroblast migration. J Biol Chem. 2019;294 (9) :2988-2996.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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