NPD8733
NPD8733 is an inhibitor of cancer cell-enhanced fibroblast migration. NPD8733 specifically binds to valosin-containing protein (VCP) /p97, a member of the ATPase-associated with diverse cellular activities (AAA+) protein family. NPD8733 has the potential for the research of cancer diseases[1].
Product Specifications
CAS Number
696655-62-6
UNSPSC
12352005
Target
P97
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/npd8733.html
Purity
99.92
Solubility
DMSO : 116.67 mg/mL (ultrasonic)
Smiles
CC(NC1=C(C(C2=CC=C(OC)C=C2)=O)OC3=CC=CC=C13)=O
Molecular Formula
C18H15NO4
Molecular Weight
309.32
References & Citations
[1]Suvarna K, et al. A small-molecule ligand of valosin-containing protein/p97 inhibits cancer cell-accelerated fibroblast migration. J Biol Chem. 2019;294 (9) :2988-2996.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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