(±) -Enterodiol

(±) -Enterodiol is the racemate of Enterodiol (HY-108695) . Enterodiol is transformed by human intestinal bacteria from lignans contained in various whole-grain cereals, nuts, legumes, flaxseed, and vegetables. Enterodiol has an apoptotic effect in colorectal cancer (CRC) cells. Enterodiol has anti-cancer activities[1][2].

Product Specifications

CAS Number

[77756-22-0]

UNSPSC

12352005

Target

Apoptosis; Endogenous Metabolite

Type

Natural Products

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/racemic-enterodiol.html

Solubility

10 mM in DMSO

Smiles

OC1=CC=CC(C[C@@H](CO)[C@H](CO)CC2=CC(O)=CC=C2)=C1

Molecular Formula

C18H22O4

Molecular Weight

302.36

References & Citations

[1]Shin MK, et al. Apoptotic effect of enterodiol, the final metabolite of edible lignans, in colorectal cancer cells. J Sci Food Agric. 2019 Mar 30;99 (5) :2411-2419. |[2]Liu H, et al. Enterolactone has stronger effects than enterodiol on ovarian cancer. J Ovarian Res. 2017 Jul 24;10 (1) :49.