CTLA-4 mAb (9H10), InVivoPure+
The CTLA-4 mAb clone 9H10 antibody recognizes cytotoxic T lymphocyte antigen 4 (CTLA-4) also known as CD152. Antibody 9H10 has shown specific reactivity against CTLA-4 Ig but not CD4 lg, as well as the ability to block CTLA-4 Ig by binding to B7 transfected cells. Staining of activated T cells, but not freshly isolated T cells, is reported, as well as the ability to stain a CTLA 4 transfectant but not control transfectants . The CTLA-4 mAb (9H10) antibody has shown effectiveness in reducing tumor growth and metastasis in preclinical models . These characteristics make the 9H10 antibody a reliable tool for identifying and studying CTLA-4 in various immunological contexts.
Product Specifications
Product Name Alternative
Anti-Mouse CTLA-4, CD152, CTLA4, cytotoxic T-lymphocyte-associated antigen 4, Cytotoxic T-lymphocyte protein 4
UniProt
P09793
Reactivity
Mouse
Immunogen
This antibody was raised by immunizing Syrian hamsters with heat-killed Staphylococcus A bacteria coated in CTLA-4.
Target
CTLA-4
Clonality
Monoclonal
Clone
9H10
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Concentration
≥ 1 mg/ mL
Purity
≥ 95 % (CGE, reducing conditions) ≤ 5 % aggregates (analytical SEC) Endotoxin level ≤ 1 EU/mg
Form
Clear Liquid, PBS, pH 7.4, 0.2 μm sterile filtered
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
In vivo
Host or Source
Golden Hamster
Preservative
Clear Liquid, PBS, pH 7.4, 0.2 μm sterile filtered
Isotype
Syrian hamster IgG
Available Sizes
Frequently Asked Questions
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