HHS-0701
HHS-0701, a sulfur-triazole exchange (SuTEx) ligand, is a potent tyrosine-reactive prostaglandin reductase 2 (PTGR2) inhibitor. HHS-0701 blocks PTGR2 metabolism of the lipid substrate 15-Keto-PGE2[1].
Product Specifications
CAS Number
2851993-91-2
UNSPSC
12352005
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/hhs-0701.html
Purity
98.90
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(S(N2N=CN=C2)(=O)=O)C=C1)N3CCC(C4=CC=CC=C4)CC3
Molecular Formula
C20H20N4O3S
Molecular Weight
396.46
References & Citations
[1]Emmanuel K Toroitich, et al.Discovery of a Cell-Active SuTEx Ligand of Prostaglandin Reductase 2. Chembiochem. 2021 Jun 15;22 (12) :2134-2139.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
High Mobility Group Protein B2 (HMGB2) Antibody
Ethyl 2- (2-fluoro-3-methoxypyridin-4-yl) -2-oxoacetate