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PRAS40 AKT1S1 Rabbit Monoclonal Antibody

PRAS40 AKT1S1 Rabbit Monoclonal Antibody

Product Specifications

Product Name Alternative

Proline-rich AKT1 substrate 1; 40 kDa proline-rich AKT substrate; AKT1S1; PRAS40

UniProt

Q96B36

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human PRAS40 Many growth factors and hormones induce the phosphoinositide 3-kinase signaling pathway, which results in the activation of downstream effector proteins such as the serine/threonine kinase Akt. One known Akt substrate is a 40 kDa, proline-rich protein (PRAS40) that binds to 14-3-3 protein. PRAS40 also binds mTOR to transduce Akt signals to the mTOR complex.

Target

Proline-rich AKT1 substrate 1

Clonality

Monoclonal

Clone

BCEJFX3

Conjugation

Unconjugated

Field of Research

Cell Biology, Neuroscience, Protein Biochemistry, Signal Transduction

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Dilution

WB 1:500-2000 IP 1:20

Form

Liquid

Molecular Weight

58 kDa

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Tested Applications

IP, WB

Host or Source

Rabbit

Preservative

Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. *This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Isotype

Rabbit IgG

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