FIDAS-5
FIDAS-5 is a potent and orally active methionine S-adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM. FIDAS-5 effectively competes against S-adenosylmethionine (SAM) for MAT2A binding. FIDAS-5 has anticancer activities[1].
Product Specifications
CAS Number
[1391934-98-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Methionine Adenosyltransferase (MAT)
Type
Reference compound
Related Pathways
Epigenetics; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fidas-5.html
Purity
98.46
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CNC1=CC=C(/C=C/C2=C(F)C=CC=C2Cl)C=C1
Molecular Formula
C15H13ClFN
Molecular Weight
261.72
Precautions
H302, H315, H319, H335
References & Citations
[1]Zhang W, et al. Fluorinated N, N-dialkylaminostilbenes repress colon cancer by targeting methionine S-adenosyltransferase 2A. ACS Chem Biol. 2013 Apr 19;8 (4) :796-803.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
38365124 3x 1.0µg DNA
RAB8B CRISPRa sgRNA lentivector (set of three targets)(Mouse)
Ask
View Details