5-Heptadecylresorcinol
Product Specifications
UNSPSC Description
5-Heptadecylresorcinol (AR-C17), a phenolic lipid component, is also an orally active mitochondrial protector. 5-Heptadecylresorcinol improves mitochondrial function via sirtuin3 signaling pathway, thus alleviates endothelial cell damage and apoptosis. 5-Heptadecylresorcinol induces sirtuin3-mediated autophagy. 5-Heptadecylresorcinol reduces the atherosclerotic plaques in the aortic root region of mice heart. 5-Heptadecylresorcinol can be used for research of atherosclerosis prevention and obesity[1][2].
Target Antigen
Sirtuin
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage;Epigenetics
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/5-heptadecylresorcinol.html
Purity
99.83
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=CC(CCCCCCCCCCCCCCCCC)=CC(O)=C1
Molecular Weight
348.56
References & Citations
[1]Rakshit D, et al. The Pharmacological Activity of Garlic (Allium sativum) in Parkinson's Disease: From Molecular Mechanisms to the Therapeutic Potential. ACS Chem Neurosci. 2023 Mar 15;14(6):1033-1044. |[2]Yoo DY, et al. Neuroprotective effects of Z-ajoene, an organosulfur compound derived from oil-macerated garlic, in the gerbil hippocampal CA1 region after transient forebrain ischemia. Food Chem Toxicol. 2014 Oct;72:1-7.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N2673/5-Heptadecylresorcinol-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N2673/5-Heptadecylresorcinol-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
41442-57-3
Available Sizes
Curated Selection
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