Sisunatovir (hydrochloride)
Sisunatovir (RV521) hydrochloride is a potent and orally active respiratory syncytial virus (RSV) inhibitor with IC50 values of 1.4, 1.0 nM for RSV A, RSV B, respectively. Sisunatovir hydrochloride inhibits RSV infection and reduces virus titers in the lungs of mice[1].
Product Specifications
CAS Number
[1903763-83-6]
Product Name Alternative
RV521 (hydrochloride)
UNSPSC
12352005
Target
RSV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sisunatovir-hydrochloride.html
Purity
98.61
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N(C1=C2C=CC(F)=C1)CC3=NC4=CC(CN)=CC=C4N3CCCC(F)(F)F)C52CC5.[H]Cl
Molecular Formula
C23H23ClF4N4O
Molecular Weight
482.90
References & Citations
[1]Cockerill GS, et al. Discovery of Sisunatovir (RV521), an Inhibitor of Respiratory Syncytial Virus Fusion. J Med Chem. 2021 Apr 8;64 (7) :3658-3676.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
Curated Selection
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