Nifuroxazide-d4
Nifuroxazide-d4 is the deuterium labeled Nifuroxazide. Nifuroxazide is an effective inhibitor of STAT3, also exerts potent anti-tumor and anti-metastasis activity.
Product Specifications
CAS Number
1188487-83-3
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Antibiotic; Bacterial; Isotope-Labeled Compounds; STAT
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; JAK/STAT Signaling; Others; Stem Cell/Wnt
Field of Research
Cancer; Infection
Solubility
10 mM in DMSO
Smiles
O=C(C1=C([2H])C([2H])=C(C([2H])=C1[2H])O)N/N=C/C2=CC=C([N+]([O-])=O)O2
Molecular Formula
C12H5D4N3O5
Molecular Weight
279.24
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Nelson EA, et al. Nifuroxazide inhibits survival of multiple myeloma cells by directly inhibiting STAT3. Blood. 2008 Dec 15;112 (13) :5095-102.|[3]Zhu Y, et al. Nifuroxazide exerts potent anti-tumor and anti-metastasis activity in melanoma. Sci Rep. 2016 Feb 2;6:20253.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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