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Sonrotoclax

Sonrotoclax is a potent, orally active Bcl2 inhibitor. Sonrotoclax has effective cell killing effect against a variety of lymphoma and leukemia cell lines[1].

Product Specifications

CAS Number

[2383086-06-2]

Product Name Alternative

BGB 11417

UNSPSC

12352005

Target

Bcl-2 Family

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sonrotoclax.html

Concentration

10mM

Purity

99.61

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C1=C(C=CC=C1)[C@H]2N(CCC2)C3CC4(CCN(C5=CC(OC6=CN=C(NC=C7)C7=C6)=C(C=C5)C(NS(=O)(C8=CC([N+]([O-])=O)=C(C=C8)NC[C@@H]9CC[C@@](O)(CC9)C)=O)=O)CC4)C3)C

Molecular Formula

C49H59N7O7S

Molecular Weight

890.10

References & Citations

[1]Nan HU, et, al. Methods of cancer treatment using bcl-2 inhibitor. WO2021110102A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 3

Available Sizes

Curated Selection

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