Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

IL-17A, Human (Biotinylated, HEK293, His-Avi)

IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides, cytokines, chemokines, and matrix metalloproteinases[1][2]. IL-17A Protein, Human (Biotinylated, HEK293, His-Avi) is a biotinylated recombinant human IL-17A protein with His tag and Avi tag at the C-terminus and is expressed in HEK293 cells.

Product Specifications

Product Name Alternative

IL-17A Protein, Human (Biotinylated, HEK293, His-Avi), Human, HEK293

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/il-17a-protein-human-biotinylated-132a-a-hek293-his-avi.html

Purity

95.00

Molecular Formula

3605 (Gene_ID) Q16552 (G24-A155) (Accession)

Molecular Weight

Approximately 16-30 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

References & Citations

[1]Chen K, et al. Interluekin-17A (IL17A) . Gene. 2017 May 30;614:8-14.|[2]Iwakura Y, et al. The roles of IL-17A in inflammatory immune responses and host defense against pathogens. Immunol Rev. 2008 Dec;226:57-79.|[3]Cua DJ, et al. Innate IL-17-producing cells: the sentinels of the immune system. Nat Rev Immunol. 2010 Jul;10 (7) :479-89.|[4]Wright JF, et al. The human IL-17F/IL-17A heterodimeric cytokine signals through the IL-17RA/IL-17RC receptor complex. J Immunol. 2008 Aug 15;181 (4) :2799-805.|[5]Kinoshita H, et al. Cytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stimulated with double-stranded RNA. J Allergy Clin Immunol. 2009 Jan;123 (1) :179-86.|[6]Henness S, et al. IL-17A acts via p38 MAPK to increase stability of TNF-alpha-induced IL-8 mRNA in human ASM. Am J Physiol Lung Cell Mol Physiol. 2006 Jun;290 (6) :L1283-90.

Shipping Conditions

Room temperature in continental US; may vary elsewhere.

Storage Conditions

Stored at -20°C for 2 years

Scientific Category

Recombinant Proteins

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

LPLUNC1 siRNA (m)
sc-149023 10 µM

LPLUNC1 siRNA (m)

Sign In for Pricing
View Details
Lentiviral mouse Npdc1 shRNA (UAS) - Lentiviral mouse Npdc1 shRNA (UAS, RFP) (100)
GTR15258612 1 Vial

Lentiviral mouse Npdc1 shRNA (UAS) - Lentiviral mouse Npdc1 shRNA (UAS, RFP) (100)

Sign In for Pricing
View Details
Atg16l1 3'UTR Lenti-reporter-Luc Vector
12629084 1.0 µg

Atg16l1 3'UTR Lenti-reporter-Luc Vector

Sign In for Pricing
View Details
MNK1 Antibody
MBS9504481-01 0.05 mL

MNK1 Antibody

Sign In for Pricing
View Details
MNK1 Antibody
MBS9504481-02 0.1 mL

MNK1 Antibody

Sign In for Pricing
View Details
MNK1 Antibody
MBS9504481-03 5x 0.1 mL

MNK1 Antibody

Sign In for Pricing
View Details